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| 05.04.2025 | 16:00 | Pumas UNAM | - | Deportivo Toluca | 1:1 (0:1) | |
| 16:00 | Puebla FC | - | CF América | 1:1 (1:0) | ||
| 16:00 | Club Necaxa | - | Cruz Azul | 2:2 (1:0) | ||
| 16:00 | FC Juárez | - | CF Pachuca | 0:3 (0:1) | ||
| 16:00 | Deportivo Guadalajara | - | Atlas Guadalajara | 2:2 (1:1) | ||
| 18:30 | Club León | - | CF Monterrey | 1:2 (1:1) | ||
| 18:30 | Santos Laguna | - | UANL Tigres | 6:2 (2:2) | ||
| 19:30 | Mazatlán FC | - | Club Tijuana | 2:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo Toluca | 12 | 7 | 4 | 1 | 23:9 | 14 | 27 |
| 2 |
|
CF Pachuca | 12 | 7 | 3 | 2 | 26:11 | 15 | 25 |
| 3 |
|
Santos Laguna | 12 | 7 | 1 | 4 | 30:18 | 12 | 24 |
| 4 |
|
CF Monterrey | 12 | 7 | 2 | 3 | 28:18 | 10 | 24 |
| 5 |
|
Pumas UNAM | 11 | 6 | 2 | 3 | 12:10 | 2 | 22 |
| 6 |
|
Atlético San Luis | 11 | 6 | 1 | 4 | 20:21 | -1 | 21 |
| 7 |
|
CF América | 12 | 4 | 3 | 5 | 14:14 | 0 | 20 |
| 8 |
|
Deportivo Guadalajara | 12 | 3 | 5 | 4 | 18:23 | -5 | 18 |
| 9 |
|
Atlas Guadalajara | 11 | 3 | 4 | 4 | 16:22 | -6 | 18 |
| 10 |
|
Mazatlán FC | 11 | 3 | 4 | 4 | 11:10 | 1 | 17 |
| 11 |
|
UANL Tigres | 11 | 4 | 3 | 4 | 16:19 | -3 | 17 |
| 12 |
|
Cruz Azul | 11 | 2 | 6 | 3 | 9:14 | -5 | 16 |
| 13 |
|
Puebla FC | 11 | 1 | 7 | 3 | 11:18 | -7 | 15 |
| 14 |
|
Club Necaxa | 12 | 3 | 3 | 6 | 14:20 | -6 | 13 |
| 15 |
|
FC Juárez | 12 | 2 | 4 | 6 | 9:16 | -7 | 13 |
| 16 |
|
Club León | 12 | 2 | 6 | 4 | 15:17 | -2 | 12 |
| 17 |
|
Club Tijuana | 12 | 3 | 2 | 7 | 13:19 | -6 | 12 |
| 18 |
|
Gallos Blancos | 11 | 1 | 6 | 4 | 8:14 | -6 | 12 |
