1. Jornada
21.08.2021 AEK Larnaca AEK Larnaca - Doxa Katokopias Doxa Katokopias -:-
21.08.2021 Apollon Limassol Apollon Limassol - Ethnikos Achna Ethnikos Achna -:-
21.08.2021 Olympiacos Nikosia Olympiacos Nikosia - Aris Limassol FC Aris Limassol FC -:-
21.08.2021 Omonia Nikosia Omonia Nikosia - AEL Limassol AEL Limassol -:-
21.08.2021 PAEEK PAEEK - Anorthosis Famagusta Anorthosis Famagusta -:-
21.08.2021 Paphos FC Paphos FC - APOEL Nikosia APOEL Nikosia -:-
2. Jornada
11.09.2021 Ethnikos Achna Ethnikos Achna - PAEEK PAEEK -:-
11.09.2021 AEK Larnaca AEK Larnaca - Omonia Nikosia Omonia Nikosia -:-
11.09.2021 AEL Limassol AEL Limassol - Paphos FC Paphos FC -:-
11.09.2021 APOEL Nikosia APOEL Nikosia - Olympiacos Nikosia Olympiacos Nikosia -:-
11.09.2021 Aris Limassol FC Aris Limassol FC - Apollon Limassol Apollon Limassol -:-
11.09.2021 Doxa Katokopias Doxa Katokopias - Anorthosis Famagusta Anorthosis Famagusta -:-