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| 08.05.2021 | 16:00 | Ballymena United | - | PSNI FC | 5:0 | |
| 16:00 | Carrick Rangers | - | Bangor FC | 3:1 pn. | ||
| 16:00 | Dergview FC | - | St. James' Swifts | 2:0 | ||
| 16:00 | Knockbreda FC | - | Crusaders FC | 0:5 | ||
| 16:00 | Larne FC | - | Dollingstown FC | 8:1 | ||
| 16:00 | Linfield FC | - | Dungannon Swifts | 5:2 | ||
| 16:00 | Loughgall FC | - | Warrenpoint Town | 1:0 | ||
| 18:30 | Glentoran FC | - | Cliftonville FC | 1:0 |
