| 1. Jornada | 18.02.2022 | Wexford FC | - | Treaty United | 1:5 |  |
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| 2. Jornada | 25.02.2022 | Cobh Ramblers | - | Wexford FC | 2:3 | ||||
| 3. Jornada | 04.03.2022 | Wexford FC | - | Athlone Town | 2:1 |  |
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| 14. Jornada | 02.05.2022 | Wexford FC | - | Bray Wanderers | 1:1 | ||||
| 15. Jornada | 07.05.2022 | Longford Town | - | Wexford FC | 2:1 | ||||
| 16. Jornada | 13.05.2022 | Wexford FC | - | Galway United | 0:4 | ||||
| 17. Jornada | 20.05.2022 | Cork City | - | Wexford FC | 1:1 | |
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| 19. Jornada | 10.06.2022 | Wexford FC | - | Treaty United | 1:1 | ||||
| 20. Jornada | 17.06.2022 | Cobh Ramblers | - | Wexford FC | 0:3 | ||||
| 21. Jornada | 24.06.2022 | Wexford FC | - | Longford Town | 2:1 | ||||
| 22. Jornada | 27.06.2022 | Bray Wanderers | - | Wexford FC | 2:2 | |
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| 29. Jornada | 20.08.2022 | Longford Town | - | Wexford FC | 1:0 | ||||
| 30. Jornada | 02.09.2022 | Wexford FC | - | Waterford FC | 2:2 | |
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| 31. Jornada | 09.09.2022 | Athlone Town | - | Wexford FC | 2:0 | ||||
| 33. Jornada | 30.09.2022 | Wexford FC | - | Bray Wanderers | 4:2 | |
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| 34. Jornada | 07.10.2022 | Cork City | - | Wexford FC | 0:0 | ||||
| 35. Jornada | 14.10.2022 | Wexford FC | - | Galway United | 0:0 | ||||
| 36. Jornada | 21.10.2022 | Treaty United | - | Wexford FC | 0:2 |
Irlanda