| 1. Jornada | 10.01.2021 | Deportivo Toluca [Sub 20] | - | Gallos Blancos [Sub 20] | 1:2 | ||||
| 2. Jornada | 16.01.2021 | Deportivo Guadalajara [Sub 20] | - | Deportivo Toluca [Sub 20] | 5:3 |  |
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| 3. Jornada | 24.01.2021 | Deportivo Toluca [Sub 20] | - | Club Necaxa [Sub 20] | 3:0 | |
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| 4. Jornada | 31.01.2021 | Club Tijuana [Sub 20] | - | Deportivo Toluca [Sub 20] | 1:2 | ||||
| 5. Jornada | 07.02.2021 | Deportivo Toluca [Sub 20] | - | Mazatlán FC [Sub 20] | 3:1 | |
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| 6. Jornada | 14.02.2021 | Deportivo Toluca [Sub 20] | - | Pumas UNAM [Sub 20] | 2:2 | |
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| 7. Jornada | 20.02.2021 | Cruz Azul [Sub 20] | - | Deportivo Toluca [Sub 20] | 0:3 | |
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| 8. Jornada | 27.02.2021 | Deportivo Toluca [Sub 20] | - | Atlas Guadalajara [Sub 20] | 0:1 | ||||
| 11. Jornada | 14.03.2021 | Deportivo Toluca [Sub 20] | - | CF Pachuca [Sub 20] | 2:1 | |
México