| 2. Jornada | 22.02.2022 | Deportes Temuco | - | Santiago Wanderers | 1:0 | ||||
| 3. Jornada | 02.03.2022 | Santiago Wanderers | - | Santiago Morning | 2:2 | ||||
| 4. Jornada | 10.03.2022 | San Luis | - | Santiago Wanderers | 1:1 | ||||
| 5. Jornada | 17.03.2022 | Santiago Wanderers | - | Rangers | 1:3 | ||||
| 10. Jornada | 21.04.2022 | Deportes Melipilla | - | Santiago Wanderers | 2:0 | ||||
| 12. Jornada | 01.05.2022 | Recoleta | - | Santiago Wanderers | 1:2 |
Chile