| 6. Jornada | 05.09.2020 | Deportes Melipilla | - | Unión San Felipe | 0:1 |  |
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| 8. Jornada | 13.09.2020 | San Luis | - | Deportes Melipilla | 1:1 | |
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| 9. Jornada | 16.09.2020 | Deportes Melipilla | - | Cobreloa | 1:1 | ||||
| 17. Jornada | 04.11.2020 | Ñublense | - | Deportes Melipilla | 4:0 |  |
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| 18. Jornada | 08.11.2020 | Deportes Melipilla | - | San Luis | 3:0 | ||||
| 20. Jornada | 17.11.2020 | Deportes Melipilla | - | CD Magallanes | 0:0 | ||||
| 26. Jornada | 18.12.2020 | Santiago Morning | - | Deportes Melipilla | 0:3 | ||||
| 27. Jornada | 24.12.2020 | Deportes Melipilla | - | Santa Cruz | 0:0 | ||||
| 28. Jornada | 30.12.2020 | Cobreloa | - | Deportes Melipilla | 0:0 | |
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| 29. Jornada | 12.01.2021 | Deportes Melipilla | - | Barnechea | 3:1 |
Chile