| 19. Jornada | 22.02.2021 | NK Osijek II | - | Hrvatski Dragovoljac | 0:0 |  |
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| 20. Jornada | 28.02.2021 | NK Croatia Zmijavci | - | NK Osijek II | 1:0 | ||||
| 21. Jornada | 06.03.2021 | NK Junak Sinj | - | NK Osijek II | 1:1 | |
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| 22. Jornada | 13.03.2021 | NK Osijek II | - | NK Dugopolje | 2:0 | ||||
| 23. Jornada | 19.03.2021 | NK Međimurje | - | NK Osijek II | 0:1 | ||||
| 26. Jornada | 17.04.2021 | NK Osijek II | - | NK Opatija | 1:0 | |
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| 27. Jornada | 28.04.2021 | Dinamo Zagreb II | - | NK Osijek II | 3:0 | ||||
| 29. Jornada | 02.05.2021 | Hajduk Split II | - | NK Osijek II | 4:3 | ||||
| 30. Jornada | 08.05.2021 | NK Osijek II | - | NK Sesvete | 0:3 | ||||
| 31. Jornada | 12.05.2021 | NK Solin | - | NK Osijek II | 4:3 | ||||
| 32. Jornada | 16.05.2021 | NK Osijek II | - | NK Rudeš | 2:3 | ||||
| 33. Jornada | 22.05.2021 | HNK Cibalia | - | NK Osijek II | 2:2 | |
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| 34. Jornada | 29.05.2021 | NK Osijek II | - | NK Dubrava | 0:5 |
Croacia