| 20. Jornada | 20.02.2022 | APS Zakynthos | - | Irodotos | 1:0 | ||||
| 12. Jornada | 23.02.2022 | APS Zakynthos | - | Ergotelis | 2:0 | ||||
| 21. Jornada | 27.02.2022 | Levadiakos | - | APS Zakynthos | 4:0 | ||||
| 22. Jornada | 06.03.2022 | APS Zakynthos | - | AS Rhodos | 0:3 |  |
|||
| 23. Jornada | 09.03.2022 | AO Episkopi | - | APS Zakynthos | 1:0 |  |
|||
| 24. Jornada | 13.03.2022 | APS Zakynthos | - | AE Kifisias | 1:1 | ||||
| 17. Jornada | 16.03.2022 | APS Zakynthos | - | OFI Ierapetra | 1:1 | ||||
| 25. Jornada | 19.03.2022 | AEK Athen II | - | APS Zakynthos | 1:0 | ||||
| 26. Jornada | 27.03.2022 | APS Zakynthos | - | PS Kalamata | 1:1 | ||||
| 27. Jornada | 30.03.2022 | Panathinaikos II | - | APS Zakynthos | 1:1 | |
|||
| 28. Jornada | 03.04.2022 | APS Zakynthos | - | AE Karaiskakis | 2:0 | ||||
| 29. Jornada | 06.04.2022 | Ergotelis | - | APS Zakynthos | 1:0 | ||||
| 30. Jornada | 10.04.2022 | APS Zakynthos | - | Asteras Vlachioti | 1:1 | ||||
| 31. Jornada | 13.04.2022 | Diagoras FC | - | APS Zakynthos | 2:0 | ||||
| 32. Jornada | 17.04.2022 | APS Zakynthos | - | PAE Chania | 3:1 | ||||
| 34. Jornada | 01.05.2022 | OFI Ierapetra | - | APS Zakynthos | 5:1 |
Grecia