| 2. Jornada | 14.08.2021 | FC Rodange 91 | - | RFCU Luxemburg | 0:1 | ||||
| 3. Jornada | 21.08.2021 | RFCU Luxemburg | - | RM Hamm Benfica | 1:0 |  |
|||
| 4. Jornada | 28.08.2021 | FC Wiltz 71 | - | RFCU Luxemburg | 2:3 |  |
|||
| 5. Jornada | 12.09.2021 | RFCU Luxemburg | - | F91 Dudelange | 3:4 | ||||
| 10. Jornada | 23.10.2021 | RFCU Luxemburg | - | US Mondorf | 2:1 | ||||
| 11. Jornada | 07.11.2021 | Etzella Ettelbruck | - | RFCU Luxemburg | 1:2 | |
|||
| 20. Jornada | 06.03.2022 | RFCU Luxemburg | - | Jeunesse Esch | 0:0 | ||||
| 22. Jornada | 19.03.2022 | RFCU Luxemburg | - | Progrès Niedercorn | 3:3 | |
|||
| 23. Jornada | 02.04.2022 | RFCU Luxemburg | - | Union Titus Pétange | 0:0 | |
|||
| 27. Jornada | 30.04.2022 | RFCU Luxemburg | - | Victoria Rosport | 2:1 | |
Senegal