| 5. Jornada | 05.02.2022 | Club Necaxa [Sub 16] | - | Puebla FC [Sub 16] | 0:0 | ||||
| 3. Jornada | 09.02.2022 | CF América [Sub 16] | - | Puebla FC [Sub 16] | 1:0 | ||||
| 11. Jornada | 19.03.2022 | Puebla FC [Sub 16] | - | CF Pachuca [Sub 16] | 0:4 | ||||
| 18. Jornada | 07.05.2022 | Pumas UNAM [Sub 16] | - | Puebla FC [Sub 16] | 1:1 |
México