| 3. Jornada | 25.01.2025 | Santos Laguna [Sub 19] | - | CF América [Sub 19] | 3:0 | ||||
| 4. Jornada | 29.01.2025 | FC Juárez [Sub 19] | - | Santos Laguna [Sub 19] | 0:1 | ||||
| 6. Jornada | 07.02.2025 | Club Necaxa [Sub 19] | - | Santos Laguna [Sub 19] | 1:1 |  |
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| 7. Jornada | 14.02.2025 | Mazatlán FC [Sub 19] | - | Santos Laguna [Sub 19] | 3:0 | ||||
| 9. Jornada | 19.02.2025 | Santos Laguna [Sub 19] | - | Cruz Azul [Sub 19] | 1:0 | |
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| 10. Jornada | 02.03.2025 | CF Monterrey [Sub 19] | - | Santos Laguna [Sub 19] | 1:0 | |
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| 11. Jornada | 09.03.2025 | Santos Laguna [Sub 19] | - | Club León [Sub 19] | 2:1 | ||||
| 12. Jornada | 15.03.2025 | UANL Tigres [Sub 19] | - | Santos Laguna [Sub 19] | 3:1 | |
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| 15. Jornada | 18.03.2025 | Santos Laguna [Sub 19] | - | Gallos Blancos [Sub 19] | 4:2 | ||||
| 16. Jornada | 22.03.2025 | Pumas UNAM [Sub 19] | - | Santos Laguna [Sub 19] | 3:2 | ||||
| 13. Jornada | 30.03.2025 | Santos Laguna [Sub 19] | - | Atlético San Luis [Sub 19] | 2:1 | ||||
| 17. Jornada | 20.04.2025 | Santos Laguna [Sub 19] | - | Club Tijuana [Sub 19] | 1:1 |
México