| 17. Jornada | 12.08.2021 | Jiangxi Beidamen | - | Guizhou FC | 0:1 | ||||
| 18. Jornada | 17.08.2021 | Guizhou FC | - | Nanjing City | 1:2 |  |
|||
| 19. Jornada | 05.09.2021 | Nantong Zhiyun | - | Guizhou FC | 0:1 |  |
|||
| 21. Jornada | 13.09.2021 | Zibo Cuju | - | Guizhou FC | 0:1 | |
|||
| 22. Jornada | 17.09.2021 | Guizhou FC | - | Beijing BSU | 0:0 | ||||
| 23. Jornada | 21.09.2021 | Guizhou FC | - | Nantong Zhiyun | 0:2 | ||||
| 24. Jornada | 26.09.2021 | Xinjiang Tianshan Leopard | - | Guizhou FC | 1:1 | ||||
| 25. Jornada | 30.09.2021 | Guizhou FC | - | Zibo Cuju | 1:2 | ||||
| 26. Jornada | 04.10.2021 | Beijing BSU | - | Guizhou FC | 1:1 | ||||
| 27. Jornada | 22.11.2021 | Meizhou Hakka | - | Guizhou FC | 4:2 | ||||
| 28. Jornada | 25.11.2021 | Guizhou FC | - | Zhejiang Professional | 0:0 | ||||
| 29. Jornada | 29.11.2021 | Guizhou FC | - | Kunshan FC | 0:4 |
China