| 8. Jornada | 29.08.2021 | CS Herediano | - | CS Cartaginés | 2:0 | ||||
| 9. Jornada | 09.09.2021 | AD Guanacasteca | - | CS Herediano | 2:1 | ||||
| 10. Jornada | 12.09.2021 | Municipal Grecia | - | CS Herediano | 1:2 | ||||
| 11. Jornada | 17.09.2021 | CS Herediano | - | Sporting FC | 3:0 |  |
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| 12. Jornada | 19.09.2021 | Guadalupe | - | CS Herediano | 0:2 | ||||
| 13. Jornada | 26.09.2021 | CS Herediano | - | Jicaral | 1:0 | ||||
| 14. Jornada | 04.10.2021 | CS Herediano | - | Deportivo Saprissa | 2:1 | ||||
| 15. Jornada | 13.10.2021 | Municipal Pérez Zeledón | - | CS Herediano | 0:1 | ||||
| 16. Jornada | 17.10.2021 | CS Herediano | - | LD Alajuelense | 0:0 | ||||
| 17. Jornada | 23.10.2021 | AD San Carlos | - | CS Herediano | 0:0 | ||||
| 18. Jornada | 28.10.2021 | CS Herediano | - | Santos de Guápiles | 1:1 | ||||
| 19. Jornada | 31.10.2021 | CS Cartaginés | - | CS Herediano | 0:1 | ||||
| 20. Jornada | 22.11.2021 | CS Herediano | - | AD Guanacasteca | 5:0 | ||||
| 21. Jornada | 25.11.2021 | CS Herediano | - | Municipal Grecia | 2:0 |
Costa Rica