| 14. Jornada | 08.10.2020 | San Marcos | - | Santa Cruz | 2:1 |  |
|||
| 17. Jornada | 04.11.2020 | Santa Cruz | - | Unión San Felipe | 2:1 | ||||
| 21. Jornada | 20.11.2020 | Santiago Morning | - | Santa Cruz | 2:1 | ||||
| 25. Jornada | 15.12.2020 | Rangers | - | Santa Cruz | 4:1 | ||||
| 27. Jornada | 24.12.2020 | Deportes Melipilla | - | Santa Cruz | 0:0 | ||||
| 26. Jornada | 28.12.2020 | Santa Cruz | - | Ñublense | 1:3 | ||||
| 28. Jornada | 30.12.2020 | Santa Cruz | - | San Luis | 1:3 | ||||
| 30. Jornada | 17.01.2021 | Santa Cruz | - | Deportes Valdivia | 3:2 |
Chile