| 2. Jornada | 21.08.2021 | sc Heerenveen | - | RKC Waalwijk | 3:2 | ||||
| 3. Jornada | 29.08.2021 | sc Heerenveen | - | AZ Alkmaar | 1:3 | ||||
| 4. Jornada | 12.09.2021 | FC Groningen | - | sc Heerenveen | 1:1 | ||||
| 5. Jornada | 18.09.2021 | sc Heerenveen | - | Fortuna Sittard | 1:0 | ||||
| 6. Jornada | 22.09.2021 | Feyenoord | - | sc Heerenveen | 3:1 | ||||
| 7. Jornada | 26.09.2021 | sc Heerenveen | - | FC Twente | 2:3 | ||||
| 8. Jornada | 02.10.2021 | PEC Zwolle | - | sc Heerenveen | 0:1 | ||||
| 9. Jornada | 16.10.2021 | sc Heerenveen | - | AFC Ajax | 0:2 | ||||
| 10. Jornada | 23.10.2021 | FC Utrecht | - | sc Heerenveen | 2:1 | ||||
| 12. Jornada | 06.11.2021 | NEC Nijmegen | - | sc Heerenveen | 1:1 | ||||
| 14. Jornada | 28.11.2021 | sc Heerenveen | - | PSV | 1:1 | ||||
| 15. Jornada | 04.12.2021 | Heracles Almelo | - | sc Heerenveen | 0:1 | ||||
| 16. Jornada | 11.12.2021 | sc Heerenveen | - | Sparta Rotterdam | 0:0 | ||||
| 17. Jornada | 19.12.2021 | SC Cambuur | - | sc Heerenveen | 1:2 | ||||
| 18. Jornada | 22.12.2021 | sc Heerenveen | - | Feyenoord | 0:3 | ||||
| 19. Jornada | 15.01.2022 | FC Twente | - | sc Heerenveen | 2:0 | ||||
| 20. Jornada | 22.01.2022 | sc Heerenveen | - | PEC Zwolle | 0:1 |
Suecia