| 1. Jornada | 13.01.2022 | Municipal Pérez Zeledón | - | Municipal Grecia | 1:1 | ||||
| 2. Jornada | 15.01.2022 | Municipal Grecia | - | CS Herediano | 1:1 |  |
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| 3. Jornada | 22.01.2022 | Municipal Grecia | - | Jicaral | 1:0 | |
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| 4. Jornada | 03.02.2022 | AD Guanacasteca | - | Municipal Grecia | 1:0 | |
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| 11. Jornada | 02.04.2022 | Deportivo Saprissa | - | Municipal Grecia | 0:1 |  |
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| 12. Jornada | 05.04.2022 | Municipal Grecia | - | Municipal Pérez Zeledón | 2:0 | |
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| 13. Jornada | 10.04.2022 | CS Herediano | - | Municipal Grecia | 3:1 | |
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| 14. Jornada | 16.04.2022 | Jicaral | - | Municipal Grecia | 1:1 | |
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| 16. Jornada | 24.04.2022 | Municipal Grecia | - | Guadalupe | 3:2 | |
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| 17. Jornada | 27.04.2022 | CS Cartaginés | - | Municipal Grecia | 4:0 | |
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| 18. Jornada | 01.05.2022 | AD San Carlos | - | Municipal Grecia | 2:2 | ||||
| 19. Jornada | 04.05.2022 | Municipal Grecia | - | LD Alajuelense | 1:1 | ||||
| 20. Jornada | 08.05.2022 | Sporting FC | - | Municipal Grecia | 3:2 |  |
México