| 1. Jornada | 16.01.2021 | CA Cerro | - | Peñarol | 1:1 | ||||
| 2. Jornada | 20.01.2021 | River Plate | - | CA Cerro | 1:2 | ||||
| 5. Jornada | 07.02.2021 | CA Cerro | - | Progreso | 2:0 | ||||
| 6. Jornada | 11.02.2021 | Fénix | - | CA Cerro | 3:3 | ||||
| 7. Jornada | 14.02.2021 | CA Cerro | - | Liverpool | 1:1 | ||||
| 8. Jornada | 18.02.2021 | CA Cerro | - | Defensor Sporting | 0:0 |  |
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| 9. Jornada | 22.02.2021 | Danubio | - | CA Cerro | 2:1 | ||||
| 10. Jornada | 27.02.2021 | CA Cerro | - | Nacional | 0:1 | |
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| 11. Jornada | 06.03.2021 | Boston River | - | CA Cerro | 2:0 | |
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| 12. Jornada | 13.03.2021 | CA Cerro | - | Deportivo Maldonado | 2:3 | ||||
| 13. Jornada | 19.03.2021 | Rentistas | - | CA Cerro | 0:1 | ||||
| 14. Jornada | 24.03.2021 | CA Cerro | - | Cerro Largo | 0:1 | |
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| 15. Jornada | 29.03.2021 | Montevideo Wanderers | - | CA Cerro | 1:1 |
Uruguay