| 2. Jornada | 09.07.2022 | CF Monterrey [Sub 20] | - | CF América [Sub 20] | 1:3 | ||||
| 3. Jornada | 13.07.2022 | CF América [Sub 20] | - | Deportivo Toluca [Sub 20] | 2:1 |  |
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| 13. Jornada | 06.09.2022 | CF América [Sub 20] | - | Atlético San Luis [Sub 20] | 5:0 | ||||
| 14. Jornada | 10.09.2022 | Club Necaxa [Sub 20] | - | CF América [Sub 20] | 1:2 | ||||
| 5. Jornada | 14.09.2022 | CF América [Sub 20] | - | Santos Laguna [Sub 20] | 1:0 | ||||
| 17. Jornada | 30.09.2022 | Puebla FC [Sub 20] | - | CF América [Sub 20] | 1:1 |
México