| 4. Jornada | 02.08.2018 | Club San José | - | Club Aurora | 3:2 | ||||
| 3. Jornada | 09.08.2018 | Jorge Wilstermann | - | Club San José | 3:1 | ||||
| 8. Jornada | 25.08.2018 | Club San José | - | Sport Boys Warnes | 6:0 |  |
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| 10. Jornada | 17.09.2018 | Oriente Petrolero | - | Club San José | 1:3 | ||||
| 14. Jornada | 07.10.2018 | Club San José | - | The Strongest | 3:1 | ||||
| 19. Jornada | 11.11.2018 | Universitario de Sucre | - | Club San José | 0:4 | ||||
| 22. Jornada | 18.11.2018 | Club San José | - | Real Potosí | 2:1 | ||||
| 24. Jornada | 09.12.2018 | Club San José | - | Oriente Petrolero | 5:0 | ||||
| 25. Jornada | 16.12.2018 | Blooming | - | Club San José | 1:3 |
Colombia