| 2. Jornada | 08.07.2022 | Puebla FC [Sub 20] | - | Santos Laguna [Sub 20] | 2:2 | ||||
| 3. Jornada | 15.07.2022 | Puebla FC [Sub 20] | - | Club León [Sub 20] | 3:1 | ||||
| 7. Jornada | 06.08.2022 | Puebla FC [Sub 20] | - | Pumas UNAM [Sub 20] | 1:2 | ||||
| 9. Jornada | 13.09.2022 | Puebla FC [Sub 20] | - | Club Necaxa [Sub 20] | 3:2 | ||||
| 5. Jornada | 22.09.2022 | CF Monterrey [Sub 20] | - | Puebla FC [Sub 20] | 3:3 |  |
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| 17. Jornada | 30.09.2022 | Puebla FC [Sub 20] | - | CF América [Sub 20] | 1:1 |
México