| 1. Jornada | 07.08.2021 | Guingamp (CFA) | - | FC Rouen 1899 | 0:0 | ||||
| 2. Jornada | 14.08.2021 | FC Rouen 1899 | - | AS Poissy | 0:0 | ||||
| 3. Jornada | 21.08.2021 | C'Chartres Football | - | FC Rouen 1899 | 1:2 |  |
 |
||
| 4. Jornada | 28.08.2021 | Châteaubriant Voltigeurs | - | FC Rouen 1899 | 1:0 | ||||
| 5. Jornada | 04.09.2021 | Vannes OC | - | FC Rouen 1899 | 1:2 | |
|||
| 6. Jornada | 11.09.2021 | FC Rouen 1899 | - | US Granvillaise | 0:2 | ||||
| 11. Jornada | 07.11.2021 | FC Rouen 1899 | - | US Saint-Malo | 0:1 | ||||
| 15. Jornada | 14.01.2022 | FC Rouen 1899 | - | Lorient (CFA) | 1:1 | ||||
| 16. Jornada | 22.01.2022 | FC Rouen 1899 | - | AS Poissy | 1:1 | ||||
| 18. Jornada | 12.02.2022 | Châteaubriant Voltigeurs | - | FC Rouen 1899 | 0:1 | ||||
| 17. Jornada | 26.02.2022 | FC Rouen 1899 | - | C'Chartres Football | 0:1 | ||||
| 29. Jornada | 21.05.2022 | Lorient (CFA) | - | FC Rouen 1899 | 1:1 |
Camerún