| 1. Jornada | 06.02.2016 | Fénix | - | River Plate | 1:1 | ||||
| 2. Jornada | 13.02.2016 | River Plate | - | Nacional | 0:3 | ||||
| 3. Jornada | 21.02.2016 | Sud América | - | River Plate | 2:1 | ||||
| 4. Jornada | 27.02.2016 | River Plate | - | Montevideo Wanderers | 1:1 | ||||
| 6. Jornada | 20.03.2016 | River Plate | - | Plaza Colonia | 0:1 | ||||
| 8. Jornada | 10.04.2016 | River Plate | - | Juventud de Las Piedras | 0:0 | ||||
| 9. Jornada | 24.04.2016 | Danubio | - | River Plate | 0:3 |  |
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| 10. Jornada | 30.04.2016 | River Plate | - | CA Cerro | 3:1 | ||||
| 11. Jornada | 08.05.2016 | Rentistas | - | River Plate | 2:1 | ||||
| 12. Jornada | 14.05.2016 | River Plate | - | El Tanque Sisley | 1:0 | ||||
| 13. Jornada | 22.05.2016 | Liverpool | - | River Plate | 1:0 |
Uruguay