| 17. Jornada | 04.12.2021 | Club Brugge KV | - | RFC Seraing | 3:2 |  |
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| 18. Jornada | 12.12.2021 | Club Brugge KV | - | SV Zulte Waregem | 3:0 | ||||
| 25. Jornada | 30.01.2022 | KV Kortrijk | - | Club Brugge KV | 0:1 | ||||
| 27. Jornada | 13.02.2022 | Club Brugge KV | - | Sporting Charleroi | 2:0 | ||||
| 28. Jornada | 20.02.2022 | KAS Eupen | - | Club Brugge KV | 1:3 | ||||
| 29. Jornada | 27.02.2022 | Club Brugge KV | - | Royal Antwerp FC | 4:1 | ||||
| 30. Jornada | 05.03.2022 | RFC Seraing | - | Club Brugge KV | 0:5 |
Bélgica