| 2. Jornada | 24.07.2021 | Academica Clinceni | - | CFR Cluj | 1:2 | ||||
| 4. Jornada | 06.08.2021 | CS Mioveni | - | CFR Cluj | 0:1 |  |
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| 5. Jornada | 13.08.2021 | CFR Cluj | - | Farul Constanța | 1:0 | ||||
| 6. Jornada | 21.08.2021 | Argeș Pitești | - | CFR Cluj | 0:1 | ||||
| 7. Jornada | 29.08.2021 | CFR Cluj | - | FCSB | 4:1 | ||||
| 8. Jornada | 11.09.2021 | FC Botoşani | - | CFR Cluj | 1:0 | ||||
| 9. Jornada | 20.09.2021 | CFR Cluj | - | CS Universitatea Craiova | 1:0 | |
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| 10. Jornada | 26.09.2021 | UTA Arad | - | CFR Cluj | 0:1 | |
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| 11. Jornada | 03.10.2021 | CFR Cluj | - | Gaz Metan Mediaş | 2:1 | ||||
| 13. Jornada | 25.10.2021 | CFR Cluj | - | Sepsi OSK | 2:0 | ||||
| 14. Jornada | 30.10.2021 | CFR Cluj | - | FC Voluntari | 1:0 | ||||
| 23. Jornada | 31.01.2022 | CFR Cluj | - | FC Botoşani | 1:1 | ||||
| 24. Jornada | 05.02.2022 | CS Universitatea Craiova | - | CFR Cluj | 1:1 | |
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Rumania