| 1. Jornada | 30.04.2022 | Villa Española | - | Rampla Juniors | 3:2 | ||||
| 2. Jornada | 08.05.2022 | Rampla Juniors | - | Juventud de Las Piedras | 0:1 | ||||
| 3. Jornada | 16.05.2022 | Racing | - | Rampla Juniors | 1:0 |  |
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| 4. Jornada | 21.05.2022 | Rampla Juniors | - | Uruguay Montevideo | 1:2 | ||||
| 5. Jornada | 25.05.2022 | Rampla Juniors | - | Progreso | 1:1 |  |
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| 12. Jornada | 24.07.2022 | Rampla Juniors | - | Villa Española | 1:0 | ||||
| 13. Jornada | 31.07.2022 | Juventud de Las Piedras | - | Rampla Juniors | 1:2 | ||||
| 14. Jornada | 07.08.2022 | Rampla Juniors | - | Racing | 1:0 | |
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| 15. Jornada | 13.08.2022 | Uruguay Montevideo | - | Rampla Juniors | 0:4 |  |
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| 16. Jornada | 20.08.2022 | Progreso | - | Rampla Juniors | 0:1 | ||||
| 17. Jornada | 23.08.2022 | Rampla Juniors | - | La Luz | 0:3 | ||||
| 18. Jornada | 29.08.2022 | Atenas | - | Rampla Juniors | 1:1 | ||||
| 19. Jornada | 03.09.2022 | Rampla Juniors | - | CA Cerro | 2:2 | |
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| 20. Jornada | 11.09.2022 | Sud América | - | Rampla Juniors | 2:1 | ||||
| 21. Jornada | 18.09.2022 | Rampla Juniors | - | Central Español | 3:0 | |
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| 22. Jornada | 25.09.2022 | Miramar Misiones | - | Rampla Juniors | 1:3 | |
Uruguay