| 2. Jornada | 28.07.2018 | Puebla FC | - | Deportivo Toluca | 2:1 | ||||
| 5. Jornada | 19.08.2018 | Club Necaxa | - | Puebla FC | 2:2 | ||||
| 7. Jornada | 26.08.2018 | CF Pachuca | - | Puebla FC | 2:0 | ||||
| 8. Jornada | 01.09.2018 | Puebla FC | - | CF Monterrey | 2:1 | ||||
| 9. Jornada | 16.09.2018 | Gallos Blancos | - | Puebla FC | 0:1 | ||||
| 10. Jornada | 22.09.2018 | Puebla FC | - | CF América | 2:3 | ||||
| 11. Jornada | 30.09.2018 | Pumas UNAM | - | Puebla FC | 2:2 | ||||
| 12. Jornada | 08.10.2018 | Puebla FC | - | Lobos BUAP | 2:2 |  |
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| 15. Jornada | 03.11.2018 | Puebla FC | - | Deportivo Guadalajara | 2:2 |
Uruguay