| 18. Jornada | 31.01.2022 | KF Skënderbeu | - | KF Teuta Durrës | 0:1 | ||||
| 19. Jornada | 05.02.2022 | KF Tiranë | - | KF Skënderbeu | 3:2 | ||||
| 20. Jornada | 14.02.2022 | KF Skënderbeu | - | FK Partizani | 1:2 | ||||
| 21. Jornada | 19.02.2022 | Egnatia Rrogozhine | - | KF Skënderbeu | 2:0 |  |
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| 22. Jornada | 25.02.2022 | KF Skënderbeu | - | FK Vllaznia | 2:2 | ||||
| 23. Jornada | 03.03.2022 | KS Kastrioti | - | KF Skënderbeu | 1:0 | |
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| 24. Jornada | 08.03.2022 | KF Skënderbeu | - | Dinamo Tiranë | 0:1 | ||||
| 25. Jornada | 13.03.2022 | KF Laçi | - | KF Skënderbeu | 0:0 | ||||
| 26. Jornada | 20.03.2022 | KF Skënderbeu | - | FK Kukësi | 1:1 | ||||
| 27. Jornada | 03.04.2022 | KF Teuta Durrës | - | KF Skënderbeu | 0:0 | ||||
| 28. Jornada | 10.04.2022 | KF Skënderbeu | - | KF Tiranë | 0:4 | ||||
| 29. Jornada | 17.04.2022 | FK Partizani | - | KF Skënderbeu | 0:0 | ||||
| 30. Jornada | 24.04.2022 | KF Skënderbeu | - | Egnatia Rrogozhine | 0:1 | ||||
| 31. Jornada | 30.04.2022 | FK Vllaznia | - | KF Skënderbeu | 1:0 | ||||
| 32. Jornada | 04.05.2022 | KF Skënderbeu | - | KS Kastrioti | 2:0 | |
Albania