| 1. Jornada | 04.02.2018 | Leones FC | - | América de Cali | 1:2 | ||||
| 2. Jornada | 11.02.2018 | Alianza Petrolera | - | Leones FC | 1:0 | ||||
| 3. Jornada | 14.02.2018 | Leones FC | - | Jaguares de Córdoba | 0:0 | ||||
| 4. Jornada | 18.02.2018 | Atlético Bucaramanga | - | Leones FC | 2:2 |  |
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| 5. Jornada | 24.02.2018 | Leones FC | - | Deportivo Pasto | 2:1 | ||||
| 6. Jornada | 03.03.2018 | Envigado FC | - | Leones FC | 1:1 | ||||
| 7. Jornada | 07.03.2018 | Leones FC | - | Atlético Huila | 0:0 | ||||
| 8. Jornada | 14.03.2018 | Boyacá Chicó | - | Leones FC | 1:1 | |
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| 9. Jornada | 19.03.2018 | Leones FC | - | Independiente Medellín | 0:2 | ||||
| 15. Jornada | 15.04.2018 | Leones FC | - | Millonarios | 2:1 | |
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| 16. Jornada | 18.04.2018 | Leones FC | - | Deportes Tolima | 0:1 |
Colombia