| 26. Jornada | 11.02.2022 | Almere City FC | - | FC Emmen | 0:0 | ||||
| 27. Jornada | 21.02.2022 | Jong Ajax | - | Almere City FC | 1:3 | ||||
| 28. Jornada | 25.02.2022 | Almere City FC | - | VVV-Venlo | 0:1 | ||||
| 29. Jornada | 07.03.2022 | FC Utrecht (J) | - | Almere City FC | 1:2 | ||||
| 30. Jornada | 11.03.2022 | Almere City FC | - | Helmond Sport | 3:0 | ||||
| 31. Jornada | 18.03.2022 | Almere City FC | - | FC Den Bosch | 2:0 | ||||
| 32. Jornada | 27.03.2022 | MVV | - | Almere City FC | 0:3 | ||||
| 33. Jornada | 01.04.2022 | Almere City FC | - | SBV Excelsior | 3:0 | ||||
| 34. Jornada | 08.04.2022 | FC Eindhoven | - | Almere City FC | 3:1 | ||||
| 35. Jornada | 16.04.2022 | Almere City FC | - | NAC Breda | 1:2 | ||||
| 36. Jornada | 22.04.2022 | TOP Oss | - | Almere City FC | 2:3 |  |
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| 37. Jornada | 29.04.2022 | ADO Den Haag | - | Almere City FC | 1:0 | ||||
| 38. Jornada | 06.05.2022 | Almere City FC | - | AZ Alkmaar (J) | 0:3 |
Países Bajos