| 14. Jornada | 08.08.2021 | Nacional Potosí | - | Independiente Petrolero | 1:2 | ||||
| 16. Jornada | 19.08.2021 | Oriente Petrolero | - | Independiente Petrolero | 1:2 |  |
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| 19. Jornada | 19.09.2021 | Independiente Petrolero | - | Bolívar | 2:1 | |
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| 21. Jornada | 27.09.2021 | Independiente Petrolero | - | Club Aurora | 3:0 | ||||
| 22. Jornada | 21.10.2021 | Atlético Palmaflor | - | Independiente Petrolero | 0:0 | ||||
| 23. Jornada | 24.10.2021 | Independiente Petrolero | - | Real Tomayapo | 1:0 | ||||
| 24. Jornada | 27.10.2021 | Always Ready | - | Independiente Petrolero | 2:2 | ||||
| 30. Jornada | 12.12.2021 | CD Guabirá | - | Independiente Petrolero | 2:3 |
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