| 2. Jornada | 20.01.2025 | CF Pachuca [Sub 23] | - | Santos Laguna [Sub 23] | 0:0 | ||||
| 5. Jornada | 02.02.2025 | Santos Laguna [Sub 23] | - | Puebla FC [Sub 23] | 0:0 | ||||
| 7. Jornada | 14.02.2025 | Mazatlán FC [Sub 23] | - | Santos Laguna [Sub 23] | 1:5 | ||||
| 8. Jornada | 23.02.2025 | Santos Laguna [Sub 23] | - | Atlas Guadalajara [Sub 23] | 2:0 | ||||
| 11. Jornada | 09.03.2025 | Santos Laguna [Sub 23] | - | Club León [Sub 23] | 2:0 | ||||
| 13. Jornada | 30.03.2025 | Santos Laguna [Sub 23] | - | Atlético San Luis [Sub 23] | 1:0 | ||||
| 14. Jornada | 06.04.2025 | Deportivo Toluca [Sub 23] | - | Santos Laguna [Sub 23] | 1:0 | ||||
| 17. Jornada | 20.04.2025 | Santos Laguna [Sub 23] | - | Club Tijuana [Sub 23] | 1:0 |
México