| 2. Jornada | 16.01.2021 | Cruz Azul [Sub 20] | - | Puebla FC [Sub 20] | 1:0 | ||||
| 5. Jornada | 06.02.2021 | CF América [Sub 20] | - | Puebla FC [Sub 20] | 4:1 | ||||
| 6. Jornada | 12.02.2021 | Puebla FC [Sub 20] | - | FC Juárez [Sub 20] | 3:0 | ||||
| 8. Jornada | 26.02.2021 | Puebla FC [Sub 20] | - | Club Necaxa [Sub 20] | 3:2 | ||||
| 1. Jornada | 27.03.2021 | Puebla FC [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 2:4 | ||||
| 15. Jornada | 17.04.2021 | Atlético San Luis [Sub 20] | - | Puebla FC [Sub 20] | 5:3 |
México