| 4. Jornada | 18.03.2020 | Unión San Felipe | - | Santa Cruz | 1:1 |  |
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| 8. Jornada | 14.09.2020 | Ñublense | - | Santa Cruz | 2:2 | |
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| 10. Jornada | 23.09.2020 | San Luis | - | Santa Cruz | 0:0 |  |
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| 11. Jornada | 28.09.2020 | Santa Cruz | - | Santiago Morning | 2:1 | ||||
| 12. Jornada | 01.10.2020 | Barnechea | - | Santa Cruz | 2:3 | |
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| 13. Jornada | 05.10.2020 | Santa Cruz | - | CD Magallanes | 0:3 | ||||
| 14. Jornada | 08.10.2020 | San Marcos | - | Santa Cruz | 2:1 | ||||
| 15. Jornada | 12.10.2020 | Santa Cruz | - | Deportes Copiapó | 1:4 | ||||
| 16. Jornada | 28.10.2020 | Puerto Montt | - | Santa Cruz | 4:1 | |
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| 17. Jornada | 04.11.2020 | Santa Cruz | - | Unión San Felipe | 2:1 | ||||
| 23. Jornada | 06.12.2020 | Deportes Temuco | - | Santa Cruz | 2:1 | ||||
| 24. Jornada | 10.12.2020 | Santa Cruz | - | Cobreloa | 4:1 | ||||
| 25. Jornada | 15.12.2020 | Rangers | - | Santa Cruz | 4:1 | |
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| 28. Jornada | 30.12.2020 | Santa Cruz | - | San Luis | 1:3 |
Chile