| 1. Jornada | 03.02.2018 | River Plate | - | Boston River | 2:2 |  |
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| 2. Jornada | 10.02.2018 | Boston River | - | Montevideo Wanderers | 1:3 | |
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| 3. Jornada | 17.02.2018 | Liverpool | - | Boston River | 2:2 | ||||
| 5. Jornada | 03.03.2018 | CA Cerro | - | Boston River | 2:3 | ||||
| 6. Jornada | 10.03.2018 | Peñarol | - | Boston River | 2:1 |  |
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| 8. Jornada | 24.03.2018 | Danubio | - | Boston River | 0:0 | ||||
| 10. Jornada | 31.03.2018 | Rampla Juniors | - | Boston River | 0:0 | ||||
| 12. Jornada | 15.04.2018 | Nacional | - | Boston River | 1:0 | |
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| 13. Jornada | 22.04.2018 | Boston River | - | Progreso | 3:2 | |
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| 14. Jornada | 01.05.2018 | Defensor Sporting | - | Boston River | 2:1 |
Uruguay