| 1. Jornada | 21.07.2018 | Boston River | - | River Plate | 2:3 | ||||
| 3. Jornada | 05.08.2018 | Boston River | - | Liverpool | 1:0 |  |
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| 5. Jornada | 19.08.2018 | Boston River | - | CA Cerro | 2:3 | ||||
| 7. Jornada | 02.09.2018 | Atenas | - | Boston River | 1:0 | ||||
| 8. Jornada | 09.09.2018 | Boston River | - | Danubio | 0:0 | ||||
| 10. Jornada | 23.09.2018 | Boston River | - | Rampla Juniors | 0:0 | |
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| 11. Jornada | 07.10.2018 | Fénix | - | Boston River | 2:1 | ||||
| 12. Jornada | 14.10.2018 | Boston River | - | Nacional | 1:0 | ||||
| 13. Jornada | 21.10.2018 | Progreso | - | Boston River | 1:0 | |
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| 14. Jornada | 28.10.2018 | Boston River | - | Defensor Sporting | 3:1 | ||||
| 15. Jornada | 04.11.2018 | Racing | - | Boston River | 3:0 |
Uruguay