| 1. Jornada | 23.02.2020 | Deportes Valdivia | - | Santa Cruz | 1:0 |  |
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| 2. Jornada | 01.03.2020 | Santa Cruz | - | Rangers | 0:2 | |
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| 5. Jornada | 31.08.2020 | Santa Cruz | - | Deportes Melipilla | 2:4 | |
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| 6. Jornada | 06.09.2020 | Cobreloa | - | Santa Cruz | 0:1 | ||||
| 7. Jornada | 10.09.2020 | Santa Cruz | - | Puerto Montt | 0:1 | |
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| 9. Jornada | 20.09.2020 | Santa Cruz | - | Deportes Temuco | 0:2 | ||||
| 15. Jornada | 12.10.2020 | Santa Cruz | - | Deportes Copiapó | 1:4 | ||||
| 21. Jornada | 20.11.2020 | Santiago Morning | - | Santa Cruz | 2:1 | ||||
| 22. Jornada | 24.11.2020 | Santa Cruz | - | San Marcos | 0:2 | |
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| 27. Jornada | 24.12.2020 | Deportes Melipilla | - | Santa Cruz | 0:0 | |
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| 26. Jornada | 28.12.2020 | Santa Cruz | - | Ñublense | 1:3 |  |
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| 29. Jornada | 12.01.2021 | CD Magallanes | - | Santa Cruz | 2:0 | ||||
| 30. Jornada | 17.01.2021 | Santa Cruz | - | Deportes Valdivia | 3:2 |
Chile