| 17. Jornada | 05.02.2022 | Panathinaikos II | - | AO Episkopi | 1:2 | ||||
| 13. Jornada | 09.02.2022 | Panathinaikos II | - | AO Egaleo | 0:1 | ||||
| 18. Jornada | 12.02.2022 | Panathinaikos II | - | AE Kifisias | 1:0 | ||||
| 19. Jornada | 16.02.2022 | AEK Athen II | - | Panathinaikos II | 0:1 | ||||
| 20. Jornada | 20.02.2022 | Panathinaikos II | - | PS Kalamata | 1:2 | ||||
| 22. Jornada | 05.03.2022 | AE Karaiskakis | - | Panathinaikos II | 1:1 | ||||
| 23. Jornada | 09.03.2022 | Panathinaikos II | - | Ergotelis | 0:0 | ||||
| 24. Jornada | 12.03.2022 | Asteras Vlachioti | - | Panathinaikos II | 3:1 | ||||
| 25. Jornada | 19.03.2022 | Panathinaikos II | - | Diagoras FC | 3:0 | ||||
| 26. Jornada | 26.03.2022 | PAE Chania | - | Panathinaikos II | 2:0 | ||||
| 27. Jornada | 30.03.2022 | Panathinaikos II | - | APS Zakynthos | 1:1 |  |
Grecia