| 1. Jornada | 25.07.2021 | Spartak Trnava | - | FK Pohronie | 2:0 | ||||
| 2. Jornada | 31.07.2021 | FK Pohronie | - | MFK Zemplín Michalovce | 2:0 |  |
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| 3. Jornada | 08.08.2021 | MŠK Žilina | - | FK Pohronie | 3:1 |  |
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| 6. Jornada | 27.08.2021 | FK Pohronie | - | FC DAC 1904 | 0:3 | |
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| 7. Jornada | 11.09.2021 | FK Senica | - | FK Pohronie | 1:0 | ||||
| 8. Jornada | 18.09.2021 | Tatran Liptovský Mikuláš | - | FK Pohronie | 5:1 | |
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| 13. Jornada | 30.10.2021 | MFK Zemplín Michalovce | - | FK Pohronie | 0:2 | ||||
| 14. Jornada | 06.11.2021 | FK Pohronie | - | MŠK Žilina | 1:2 | |
Eslovaquia