| 1. Jornada | 01.08.2010 | Cercle Brugge | - | Sporting Charleroi | 1:1 | ||||
| 2. Jornada | 07.08.2010 | Sporting Charleroi | - | RSC Anderlecht | 0:0 | ||||
| 3. Jornada | 15.08.2010 | KRC Genk | - | Sporting Charleroi | 5:0 | ||||
| 10. Jornada | 02.10.2010 | SV Zulte Waregem | - | Sporting Charleroi | 1:1 | ||||
| 11. Jornada | 16.10.2010 | Sporting Charleroi | - | Sporting Lokeren | 1:2 | ||||
| 17. Jornada | 27.11.2010 | RSC Anderlecht | - | Sporting Charleroi | 4:1 | ||||
| 19. Jornada | 11.12.2010 | Gante | - | Sporting Charleroi | 2:1 |  |
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| 20. Jornada | 18.12.2010 | KAS Eupen | - | Sporting Charleroi | 1:0 | ||||
| 22. Jornada | 29.12.2010 | Club Brugge KV | - | Sporting Charleroi | 5:0 |
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