| 2. Jornada | 31.07.2021 | Esbjerg fB | - | FC Helsingør | 1:3 |  |
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| 3. Jornada | 07.08.2021 | Lyngby BK | - | Esbjerg fB | 5:0 | ||||
| 4. Jornada | 13.08.2021 | Esbjerg fB | - | AC Horsens | 0:0 | ||||
| 5. Jornada | 17.08.2021 | FC Fredericia | - | Esbjerg fB | 1:0 | ||||
| 6. Jornada | 20.08.2021 | Esbjerg fB | - | Hvidovre IF | 1:2 | |
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| 7. Jornada | 27.08.2021 | Nykøbing FC | - | Esbjerg fB | 1:1 | ||||
| 8. Jornada | 10.09.2021 | Esbjerg fB | - | Hobro IK | 2:1 | ||||
| 9. Jornada | 18.09.2021 | Esbjerg fB | - | Fremad Amager | 2:1 | |
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| 10. Jornada | 26.09.2021 | Jammerbugt FC | - | Esbjerg fB | 1:0 | ||||
| 11. Jornada | 04.10.2021 | Esbjerg fB | - | HB Køge | 2:0 | |
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| 12. Jornada | 14.10.2021 | FC Helsingør | - | Esbjerg fB | 3:0 | ||||
| 13. Jornada | 23.10.2021 | Esbjerg fB | - | FC Fredericia | 1:2 | |
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| 14. Jornada | 29.10.2021 | Hobro IK | - | Esbjerg fB | 2:6 | |
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| 15. Jornada | 05.11.2021 | Esbjerg fB | - | Jammerbugt FC | 2:2 | ||||
| 17. Jornada | 28.11.2021 | Esbjerg fB | - | Nykøbing FC | 3:0 | ||||
| 18. Jornada | 02.12.2021 | Hvidovre IF | - | Esbjerg fB | 2:0 | ||||
| 22. Jornada | 18.03.2022 | Esbjerg fB | - | Lyngby BK | 0:3 |
Dinamarca