| 4. Jornada | 28.08.2021 | F91 Dudelange | - | US Hostert | 2:2 | ||||
| 5. Jornada | 12.09.2021 | RFCU Luxemburg | - | F91 Dudelange | 3:4 | ||||
| 6. Jornada | 18.09.2021 | F91 Dudelange | - | Union Titus Pétange | 3:1 | ||||
| 8. Jornada | 26.09.2021 | F91 Dudelange | - | Etzella Ettelbruck | 6:1 | ||||
| 10. Jornada | 24.10.2021 | F91 Dudelange | - | Victoria Rosport | 4:1 |  |
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| 13. Jornada | 28.11.2021 | Swift Hesperange | - | F91 Dudelange | 1:0 | ||||
| 16. Jornada | 05.02.2022 | F91 Dudelange | - | Progrès Niedercorn | 1:2 | ||||
| 20. Jornada | 06.03.2022 | Union Titus Pétange | - | F91 Dudelange | 0:1 | ||||
| 22. Jornada | 20.03.2022 | Etzella Ettelbruck | - | F91 Dudelange | 0:4 | ||||
| 28. Jornada | 08.05.2022 | FC Rodange 91 | - | F91 Dudelange | 0:2 |  |
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