| 4. Jornada | 13.08.2010 | Hrvatski Dragovoljac | - | NK Istra 1961 | 1:1 | ||||
| 6. Jornada | 28.08.2010 | HNK Šibenik | - | NK Istra 1961 | 2:2 | ||||
| 7. Jornada | 11.09.2010 | NK Istra 1961 | - | NK Inter Zaprešić | 0:1 | ||||
| 8. Jornada | 18.09.2010 | NK Zadar | - | NK Istra 1961 | 2:0 | ||||
| 9. Jornada | 25.09.2010 | NK Istra 1961 | - | RNK Split | 0:1 |  |
|||
| 11. Jornada | 16.10.2010 | NK Istra 1961 | - | HNK Rijeka | 0:0 | ||||
| 12. Jornada | 23.10.2010 | NK Varaždin | - | NK Istra 1961 | 2:1 | ||||
| 13. Jornada | 30.10.2010 | NK Istra 1961 | - | NK Karlovac | 1:0 | ||||
| 16. Jornada | 20.11.2010 | NK Istra 1961 | - | Hajduk Split | 2:0 | ||||
| 18. Jornada | 04.12.2010 | NK Istra 1961 | - | Lokomotiva Zagreb | 2:1 |
Bosnia y Herzegovina