| 2. Jornada | 24.09.2021 | CD Zap | - | Escorpiones | 2:1 | ||||
| 3. Jornada | 02.10.2021 | Cafetaleros de Chiapas | - | CD Zap | 2:1 | ||||
| 4. Jornada | 08.10.2021 | CD Zap | - | Inter Playa | 1:5 | ||||
| 6. Jornada | 17.10.2021 | Montañeses FC | - | CD Zap | 1:0 |  |
|||
| 7. Jornada | 22.10.2021 | CD Zap | - | Leviatán FC | 3:0 |  |
|||
| 8. Jornada | 31.10.2021 | Sporting Canamy | - | CD Zap | 0:1 | ||||
| 9. Jornada | 05.11.2021 | CD Zap | - | Yalmakan FC | 1:3 | |
México