| 4. Jornada | 14.08.2021 | Jocoro FC | - | Isidro Metapán | 1:0 | ||||
| 5. Jornada | 22.08.2021 | Atlético Marte | - | Jocoro FC | 2:1 |  |
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| 8. Jornada | 11.09.2021 | Jocoro FC | - | AD Chalatenango | 3:1 | ||||
| 11. Jornada | 25.09.2021 | Jocoro FC | - | Alianza | 3:3 | ||||
| 15. Jornada | 24.10.2021 | Isidro Metapán | - | Jocoro FC | 1:1 | ||||
| 17. Jornada | 03.11.2021 | Santa Tecla FC | - | Jocoro FC | 2:1 | ||||
| 18. Jornada | 06.11.2021 | Jocoro FC | - | CD Águila | 2:2 | ||||
| 20. Jornada | 17.11.2021 | Municipal Limeño | - | Jocoro FC | 0:0 | ||||
| 21. Jornada | 21.11.2021 | Jocoro FC | - | Platense Zacatecoluca | 1:1 | ||||
| 22. Jornada | 27.11.2021 | Alianza | - | Jocoro FC | 2:0 |
El Salvador