| 12. Jornada | 05.12.2021 | AEL Limassol | - | Omonia Nikosia | 0:1 | ||||
| 13. Jornada | 13.12.2021 | Omonia Nikosia | - | AEK Larnaca | 1:1 | ||||
| 14. Jornada | 19.12.2021 | Doxa Katokopias | - | Omonia Nikosia | 2:1 | ||||
| 1. Jornada | 22.12.2021 | Omonia Nikosia | - | AEL Limassol | 1:0 | ||||
| 11. Jornada | 26.12.2021 | APOEL Nikosia | - | Omonia Nikosia | 4:2 | ||||
| 17. Jornada | 16.01.2022 | Apollon Limassol | - | Omonia Nikosia | 2:0 | ||||
| 18. Jornada | 24.01.2022 | Omonia Nikosia | - | PAEEK | 2:1 | ||||
| 19. Jornada | 29.01.2022 | Anorthosis Famagusta | - | Omonia Nikosia | 1:1 |  |
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| 20. Jornada | 07.02.2022 | Omonia Nikosia | - | Ethnikos Achna | 0:2 | ||||
| 21. Jornada | 16.02.2022 | Aris Limassol | - | Omonia Nikosia | 0:2 |  |
|
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| 22. Jornada | 25.02.2022 | Omonia Nikosia | - | APOEL Nikosia | 2:4 | |
Francia