| 1. Jornada | 16.01.2005 | Cruz Azul | - | Puebla FC | 3:1 | ||||
| 2. Jornada | 23.01.2005 | Puebla FC | - | Atlas Guadalajara | 5:2 | ||||
| 3. Jornada | 30.01.2005 | Dorados de Sinaloa | - | Puebla FC | 0:0 | ||||
| 4. Jornada | 06.02.2005 | Puebla FC | - | CF América | 2:2 |  |
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| 5. Jornada | 13.02.2005 | Santos Laguna | - | Puebla FC | 2:0 | ||||
| 6. Jornada | 20.02.2005 | Puebla FC | - | UAG Tecos | 0:3 | |
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| 7. Jornada | 27.02.2005 | Puebla FC | - | Jaguares Chiapas | 1:0 | ||||
| 8. Jornada | 06.03.2005 | CF Monterrey | - | Puebla FC | 4:1 |  |
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| 10. Jornada | 20.03.2005 | Monarcas Morelia | - | Puebla FC | 3:1 | ||||
| 11. Jornada | 02.04.2005 | Puebla FC | - | Deportivo Guadalajara | 4:1 |  |
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| 12. Jornada | 10.04.2005 | Pumas UNAM | - | Puebla FC | 1:0 | ||||
| 13. Jornada | 16.04.2005 | Puebla FC | - | Atlante | 2:1 | |
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| 14. Jornada | 21.04.2005 | CF Pachuca | - | Puebla FC | 1:1 | |
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| 16. Jornada | 01.05.2005 | Veracruz (old) | - | Puebla FC | 2:1 | ||||
| 17. Jornada | 08.05.2005 | Puebla FC | - | UANL Tigres | 0:3 |
Colombia