| 1. Jornada | 01.08.2021 | Alianza | - | Municipal Limeño | 4:1 | ||||
| 3. Jornada | 11.08.2021 | Once Municipal | - | Municipal Limeño | 4:1 | ||||
| 6. Jornada | 25.08.2021 | Municipal Limeño | - | Atlético Marte | 1:2 | ||||
| 10. Jornada | 19.09.2021 | AD Chalatenango | - | Municipal Limeño | 1:1 | ||||
| 11. Jornada | 26.09.2021 | Municipal Limeño | - | Platense Zacatecoluca | 0:1 | ||||
| 12. Jornada | 02.10.2021 | Municipal Limeño | - | Alianza | 0:3 | ||||
| 14. Jornada | 09.10.2021 | Municipal Limeño | - | Once Municipal | 1:1 | ||||
| 13. Jornada | 17.10.2021 | Luis Ángel Firpo | - | Municipal Limeño | 1:1 | ||||
| 15. Jornada | 24.10.2021 | FAS | - | Municipal Limeño | 2:1 | ||||
| 21. Jornada | 21.11.2021 | Municipal Limeño | - | AD Chalatenango | 0:3 | ||||
| 22. Jornada | 27.11.2021 | Platense Zacatecoluca | - | Municipal Limeño | 0:1 |
El Salvador