| 3. Jornada | 02.03.2022 | Santiago Wanderers | - | Santiago Morning | 2:2 |  |
|||
| 4. Jornada | 10.03.2022 | San Luis | - | Santiago Wanderers | 1:1 | ||||
| 6. Jornada | 22.03.2022 | Fernández Vial | - | Santiago Wanderers | 0:0 | ||||
| 7. Jornada | 03.04.2022 | Santiago Wanderers | - | CD Magallanes | 0:2 | ||||
| 1. Jornada | 05.06.2022 | Santiago Wanderers | - | Deportes Iquique | 2:0 | ||||
| 11. Jornada | 10.06.2022 | Santiago Wanderers | - | Unión San Felipe | 0:1 | ||||
| 18. Jornada | 02.07.2022 | Deportes Iquique | - | Santiago Wanderers | 2:1 | ||||
| 20. Jornada | 15.07.2022 | Santiago Morning | - | Santiago Wanderers | 1:2 | ||||
| 21. Jornada | 26.07.2022 | Santiago Wanderers | - | San Luis | 1:2 | ||||
| 22. Jornada | 02.08.2022 | Rangers | - | Santiago Wanderers | 1:2 | ||||
| 23. Jornada | 07.08.2022 | Santiago Wanderers | - | Fernández Vial | 2:2 | ||||
| 24. Jornada | 12.08.2022 | CD Magallanes | - | Santiago Wanderers | 0:1 | |
|||
| 19. Jornada | 17.08.2022 | Santiago Wanderers | - | Deportes Temuco | 3:0 | ||||
| 25. Jornada | 21.08.2022 | Santiago Wanderers | - | Deportes Copiapó | 1:0 | ||||
| 27. Jornada | 06.09.2022 | Santiago Wanderers | - | Deportes Melipilla | 2:2 |
Chile