| 6. Jornada | 23.08.2018 | Lobos BUAP | - | CF Monterrey | 1:2 |  |
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| 7. Jornada | 26.08.2018 | Gallos Blancos | - | Lobos BUAP | 2:0 | |
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| 8. Jornada | 02.09.2018 | Lobos BUAP | - | CF América | 0:2 | ||||
| 9. Jornada | 16.09.2018 | Pumas UNAM | - | Lobos BUAP | 4:2 | |
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| 10. Jornada | 23.09.2018 | Club León | - | Lobos BUAP | 0:1 | |
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| 12. Jornada | 08.10.2018 | Puebla FC | - | Lobos BUAP | 2:2 | ||||
| 14. Jornada | 28.10.2018 | UANL Tigres | - | Lobos BUAP | 2:2 | ||||
| 15. Jornada | 04.11.2018 | Lobos BUAP | - | Club Tijuana | 3:1 | ||||
| 16. Jornada | 11.11.2018 | Cruz Azul | - | Lobos BUAP | 2:1 | |
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| 17. Jornada | 25.11.2018 | Lobos BUAP | - | Deportivo Toluca | 2:0 |
Honduras